In this exclusive MedPage Today video, Van Karlyle Morris, MD, of the University of Texas MD Anderson Cancer Center in Houston, discusses the adoption of immunotherapy for patients with microsatellite instability [MSI]-high or deficient mismatch repair (dMMR) colorectal cancers.
Following is a transcript of his remarks:
One of the really exciting advances in recent years has been the adoption of immunotherapy in patients with MSI-high or deficient mismatch repair colorectal cancers. And while the initial data came out years ago now in patients with metastatic disease, what we’ve seen in the last year with data from dostarlimab [Jemperli] in patients with rectal cancer and with the niche data in patients with localized colon cancer, is that the benefit of immune checkpoint blockade therapy can certainly be extended, probably across all stages of patients with MSI-high colorectal cancer.
When I think about ASCO last year, we saw in a small cohort of patients from Memorial Sloan …