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Skin Cancer

Are You Eating This Food Linked to Melanoma? [Video]

Are You Eating This Food Linked to Melanoma?

We’ve known since at least as far back as 1987 that there’s a link between polyunsaturated fats and melanoma.

This study looked at the adipose tissue of people and found that people with melanoma had more polyunsaturated fats in their tissue.

Where does this fat come from?

The primary source in our diets nowadays isn’t healthy food like fish, but rather from industrial seed oils like canola, soybean, sunflower, safflower, cottonseed and grapeseed oil.

Another “hidden” source is poultry and pork raised on corn, soy and grains, because these animals accumulate the polyunsaturated fat, linoleic acid, in their tissue.

While cows are often finished on grain, their bodies don’t store linoleic acid in their tissue, making grain finished beef a healthier choice than poultry and pork.

https://pubmed.ncbi.nlm.nih.gov/3110746/

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Skin Cancer

Jeffrey Scott M.D. Mohs Surgeon and Dermatologist [Video]

Dr. Jeffrey F. Scott is a board-certified Mohs micrographic surgeon and board-certified dermatologist in the Baltimore area who focuses on Mohs micrographic surgery, complex cutaneous reconstruction after Mohs surgery, the surgical management of high-risk non-melanoma skin cancer, melanoma, and rare skin cancers, and the management of skin cancer in transplant recipients. He serves as the Director of the Cutaneous Surgery and Oncology Unit at the Johns Hopkins School of Medicine. #Dematologist #JohnsHopkins #MohsSurgeon

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Skin Cancer

Research on "molecular drills" of skin cancer cells offers hope for treatment [Video]

Institute of Cancer Research in London Gene isolates that allow melanoma cells to spread#Research #moleculardrills #skin #cancercellsThe cancer cells of the skin produce "molecular forests" to penetrate healthy tissues and spread around the body, according to research that increases the prospect of new therapies for the disease. The researchers used robotic microscopy to capture the formation of exercises by melanoma cells which were cultivated in 3D material of the skin in the laboratory. The exercises help the tumor cells to fix and puncture the holes in the cells and the surrounding structures, allowing cancer to move beyond the site where it forms and reaches other tissues and organs. "This is the first time that this type of change in cell form has been associated with any type of metastatic cancer," said Chris Bakal, professor of cancer morphodynamics at the London Cancer Research Institute. Melanoma levels have more than doubled in the United Kingdom since the 1990s, with more than 16,000 people newly diagnosed with the disease each year. At first, tumors can often be eliminated by surgeons, but cancer becomes more difficult to treat because it spreads to other parts of the body. Bakal and his colleagues cultivated melanoma cells in a 3D matrix rich in collagen, one of the main proteins found in the skin. By exhausting the genes in cancer cells one by one, they discovered a particular gene, Arhgef9, which was crucial for the formation of molecular exercises. The gene is found in all human cells, but in adults, it tends to be activated in brain cells to help them establish new connections. Much earlier in human development, the gene allows neurons to produce their own drill structures, which help cells spread through the body and wire the nervous system. By writing in the journal ISCIENCE, the researchers describe how the deactivation of the ARHGEF9 gene in the melanoma cells has destabilized molecular exercises so that cancer can no longer fix and engage in neighboring tissues. The observation increases hopes of new therapies for melanoma and possibly other cancers, such as neuroblastoma, which can spread in the same way. Although the mutations of the ARHGEF9 gene are linked to a wide range of neurological disorders, the gene is considered more important during early development than to adulthood. If this is the case, the development of drugs to inhibit the gene could block the spread of melanoma without serious side effects. "We believe that the disarmament of the exercise is likely to have a general demand," said Bakal, although it suspects that the process will not be relevant for all melanomas. Because the gene is very active in this metastatic