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Multi-omics analysis of the response to immune checkpoint inhibitors at single cell resolution [Video]

Immunotherapy has revolutionized the treatment of oncologic patients. However, the target and extent of the immunomodulatory effect of different immune checkpoint inhibitors (ICIs) have not been fully elucidated. Taking advantage of a murine model of spontaneous thyroid cancer and single cell multi-omic analysis, we investigated the effect of three different ICIs on tumor progression and CD45+ organ infiltrating cells. We uncovered a broad, specific, tunable effect of ICIs. Our findings provide unexpected insights into the immunobiology of ICIs and highlight potential strategies for the optimization of immunotherapies.

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Colon Cancer

Why do you need a Colonoscopy? To make sure you don’t die of Colon Cancer! [Video]

See all the Healthcast at https://www.biobalancehealth.com/healthcast-blog/Colon Cancer is the third most common malignancy in the US and is something you don’t want to get and there are many ways to test you to see if you have pre-cancer, cancer or polyps which are also risks for cancer. They advertise these tests that you can do yourself by testing your own poop. My family physician daughter advises our patients that those tests do not adequately test for pre-cancer or colon cancer. They might find a cancer, but they will miss more than they find.90 % of Colon cancers are diagnosed after age 50. The incidence of colon cancer in the US is 4.2% and if there is a family history in a close relative before the age of 50, the incidence doubles to 8.4%. What makes a person high risk other than family history?• Personal history of adenomas (polyps) on colonoscopy• Large adenomas (more than 1 cm)• Multiple adenomas• Flat adenomas that are difficult to remove• Adenomas that have precancerous lesions• Ulcerative colitis increased the risk dramaticallyColon cancer can progress without many signs therefore it is important to get a colonoscopy under sedation when you are 50. After that, depending on your risk factors your doctor will tell you how often you will need surveillance. Now, as for the other tests that you can do at home in between colonoscopies, my favorite is the stool guaiac test looking for microscopic blood. This blood doesn’t look red and is not visible. I used to do vaginal and rectal exams at the same time during gyn exams and would test the stool on my glove for microscopic blood (the guaiac test) by taking the sample, smearing it on a card and dropping a drop of developer on it. If it turns blue, there is microscopic blood and possibly cancer. I rarely had a positive, but if I did, a referral was made for a colonoscopy, and it was about 50% positive in my testing experience. The same test at home can be done on 3 successive stool samples and this should be a good test to do at home. They have just come out with a FIT test (fecal immunochemical test) that tests for DNA mutations of colon cells. It is more sensitive and accurate than Guaiac test but not as accurate as a colonoscopy. It was determined that the best frequency was 2 x a year.As it stands the colonoscopy is the best test, but it requires sedation and an invasive procedure, however low risk. I still recommend a colonoscopy at 50 and every 10 years thereafter. Soon I am sure this FIT do at home test will be recommended frequently to lower the number of Colonoscopies, as a matter of cost saving. High risk individuals should continue with colonoscopies until the recommendations change. Prevention is my recommendation:• Eat a fresh salad every day• Drink more than 10 -8 oz glasses of water daily• Alcohol and sodas to a minimum.• Probiotics daily• Vitamin D, and Vitamin C• Report changes in your stool to your PCP• Report any obvious blood in your stool to your PCP• Double probiotics whenever you need to take a course of antibiotics.

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Breast Cancer

Breast Cancer Awareness, Dr. Alina Mateo [Video]

Hello, I’m Dr. MateoI want to take a moment to talk about breast cancer and the importance of mammograms with you. We have seen a trend that shows that some women may have delayed breast cancer screening due to the pandemic.  I am here to say that it is important not to wait.Mammograms are fast, easy, safe and the most effective way to detect breast disease.  Typically, we recommend starting screening at 40 years of age and every year after. Additionally, it is essential to know if someone in your family has had breast cancer.  If you have a family history of breast cancer it may be recommended that you begin annual screening earlier than age 40.At Penn Medicine, we offer free mammogram screenings. And we are committed to the fight against breast cancer. Thank you for listening.#PennMedicine #BreastCancerAwareness

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Blood Cancer

Queen Elizabeth Suffered A Mini-Stroke, Dealing With Blood C-a-n-c-e-r At 95 [Video]

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Prostate Cancer

EP92: It’s Movember: Have you been screened for prostate cancer? | PUTTING DR G ON THE SPOT [Video]

Consultant urologist Dr George Lee Eng Geap, or a.k.a Dr G, talks about the genetic issue of developing prostate cancer among men besides the common causes of the cancer such as unhealthy lifestyle that we might have already known.WATCH MORE: https://thestartv.com/c/newsSUBSCRIBE: https://cutt.ly/TheStarLIKE: https://fb.com/TheStarOnline

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Skin Cancer

MELANOMA UNDER THE NAIL? 👀 [Video]

Dr. Freels DIGS under this patient’s toenail to see 🔎 if she has MELANOMA.One of the most critical conditions to keep an eye out for is the development of a melanoma under the nail.This is one of the deadliest types of cancers and catching it early is key🔑 to creating the most effective treatment plan!⚠️Melanomas, however, can look similar to a hematoma, a significantly less dangerous condition.☝️ The “ABCDE” rule is helpful in remembering the warning signs of melanoma:* Asymmetry. The shape of one-half of the mole does not match the other.* Border. The edges are ragged, notched, uneven, or blurred.* Color. Shades of black, brown, and tan may be present. * Diameter. * Evolving.Looking for some products to give your own feet a little TLC?Visit www.modernpodiatrist.com for all our must have products!🤍 Use FOOTDOC for FREE SHIPPING! 🛍SHOP REPAIR Cuticle Oil: https://www.modernpodiatrist.com/product/repair-cuticle-oil/4?cp=true&sa=true&sbp=false&q=falseTHANKS FOR WATCHING! Website: https://lexingtonkypodiatry.comProducts: https://modernpodiatrist.comFacebook: https://www.facebook.com/lexingtonpodiatry/ Instagram: https://lexingtonkypodiatry.comAmazon: https://www.amazon.com/shop/lexingtonpodiatry

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Colon Cancer

COLORECTAL CANCER IN INIDA l What is Colon Cancer? l Know more about Colon Cancer [Video]

COLORECTAL CANCER IN INIDA————————————-Colorectal cancer stands to be the third-most common cancer among men, worldwide. and In India its amongst the top 5 most frequent cases detected and reported for Cancers.More than 40K Colorectal Cancer cases detected in India in year 2020.Colorectal cancer refers to cancer in the large intestine and is also known as bowel cancer, colon cancer, or rectal cancer, depending on where the cancer cells are present and is typically affecting the colon and the rectum.to know more about cancer and to get the patient assistance for best treatments and appointments:-www.cancerounds.comCANCER ROUNDS+91-8130077375#DrRahulBhargava #colorectalcancer #coloncancer #rectalcancer #cancerpatients #cancerrounds #cancerOPD #Hematologist #aplasticanemia #leukemia #ITP #lymphoma #multiplemyeloma #cancerawareness #amenia #Bloodcancer #oncologist #Bonemarrowtransplant #bonemarrowtrasnplantation #Cancertreatements #cancertherapies

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Uncategorized

Cancer survivor, 75, becomes rollerblading celebrity in China [Video]

For more:https://news.cgtn.com/news/2021-11-12/Cancer-survivor-75-becomes-rollerblading-celebrity-in-China–158woZXwXNC/index.htmlWith fishbowls or water bottles piled up on her head while playing liuqin (a traditional Chinese stringed instrument) and singing on her rollerblades, 75-year-old Wu Xiuying became quite a sensation in northeast China’s Jilin Province in recent days with her stunning feats and unyielding spirit of battling with cancer. Wu has been roller skating for 18 years since she was diagnosed with thyroid cancer in 2003. She said that we should keep moving ahead, playing happily, despite difficult circumstances.Subscribe to us on YouTube: https://goo.gl/lP12gADownload our APP on Apple Store (iOS): https://itunes.apple.com/us/app/cctvnews-app/id922456579?l=zh&ls=1&mt=8Download our APP on Google Play (Android): https://play.google.com/store/apps/details?id=com.imib.cctv