Pancreatic cancer develops around a complex structure called stroma. Stroma serves the following functions:
Supports Cancer Cells: Stroma helps cancer cells grow, which can lead to further tumor growth and spread.
Provides Blood Vessels: Stroma contains the blood vessels needed for the nourishment of cancer cells, supporting tumor growth and nutrition.
Impacts on the Immune System: Immune cells within the stroma strive to identify and eliminate cancer cells. However, cancer cells can sometimes impair the effectiveness of the immune system, causing immune cells within the stroma to become less efficient in combating cancer.
In the treatment of pancreatic cancer, efforts are focused on diminishing the influence of stroma. Stroma can function as a barrier that shields cancer cells, making their detection and treatment more challenging. Consequently, there is ongoing research and development of drugs and therapies targeting stroma. These treatments have the potential to enhance the efficiency of reaching cancer cells and managing tumor growth effectively.
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