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Scientists find clues to how air pollution may trigger lung cancer [Video]

CNN  — 

Scientists have long known that air pollution can be linked with an increased risk of lung cancer in people who never smoked, but new research describes one mechanism that might help explain how.

The findings, presented Saturday at the European Society for Medical Oncology Presidential Symposium in Paris, suggest that air pollution can trigger lung cancer in people with no history of smoking because some air pollutant particles may promote changes in cells in the airways.

In particular, more exposure to airborne particulate matter or particle pollution– at 2.5 micrometers in diameter or smaller – can drive rapid changes in airway cells that have mutations in a gene called EGFR, which are seen in about half of people with lung cancer who have never smoked, and another gene linked to lung cancer called KRAS, according to the research, conducted by scientists at the Francis Crick Institute in London and other institutions around the …

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How to optimally sequence agents in the expanding treatment armamentarium of multiple myeloma [Video]

Ezzat El Hassadi, MD, University Hospital Waterford, Waterford, Ireland, outlines the challenges associated with treatment sequencing in multiple myeloma, commenting on the remarkable efficacy of CAR-Ts in this setting, and highlighting the possibility to incorporate CAR-T therapy earlier in the treatment algorithm of multiple myeloma. This interview was recorded virtually. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.