Common prostate cancer medications may be less safe than previously thought Disclaimer :Copyright Disclaimer under section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, comment, news reporting, teaching, scholarship, education and research.Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. https://tinyurl.com/TodaySciencology#Science #Technology #Invention #ScienceDailyMen taking either of the two most common oral medications for advanced prostate cancer who had also undergone hormone therapy to treat their disease were at higher risk of serious metabolic or cardiovascular issues than patients who were only receiving hormone therapy, Michigan Medicine researchers found. Patients taking abiraterone had 1.77 times the risk of being admitted to the emergency room or the hospital due to diabetes, hypertension or heart disease compared to those who were only on hormone therapy. Those receiving enzalutamide were at 1.22 times the risk of these issues. Compared to patients not receiving abiraterone, those taking abiraterone were also more likely to need an outpatient visit with their physician related to at least one of these health conditions. That was not the case if the man was taking enzalutamide. Abiraterone and enzalutamide were both found to be relatively safe in clinical trials, but concerns that the population of patients who participated in the trials was different than those in real-life settings prompted the researchers to take another look at the effects of the drugs. For instance, this research exclusively analyzed patients with Medicare health insurance, and the majority of men studied were significantly older than those in the drugs’ clinical trials. “Patients enrolled in clinical trials tend to be highly selected and often times do not reflect the patient population in day-to-day practice,” said Lillian Y. Lai, M.D., M.S., a National Institutes of Health T32 Urologic Oncology Research Fellow at Michigan Medicine and the first author of the study. “Trial participants also undergo stringent safety evaluations that some of our patients do not have access to. By studying adverse events in real-life settings, we can better understand the risks of these life-prolonging cancer treatments and help clinicians and patients make informed decisions regarding treatment.” Since metabolic and cardiovascular conditions tend to be under the purview of primary care providers, Lai and her fellow authors recommend team-based care that involves PCPs for patients with advanced prostate cancer as a way to manage these higher risks. “With continued expansion of the indications for abiraterone and enzalutamide to earlier stages of the disease, increasing numbers of men will be receiving these therapies for longer periods of time,” Lai said. “This will potentially amplify the scope of men affected and increase the magnitude of the risks of adverse events, making careful attention to management of these issues crucial.” Other authors include Mary K. Oerline, M.S.; Megan E.V. Caram, M.D., M.S.; Phoebe A. Tsao, M.D.; Samuel R. Kaufman, M.A.; Brent K. Hollenbeck, M.D., M.S.; and Vahakn B. Shahinian, M.D., M.S. make a difference: sponsored opportunity Story Source: Materials provided by Michigan Medicine – University of Michigan. Original written by Mary Clare Fischer. Note: Content may be edited for style and length. Journal Reference: Lillian Y Lai, Mary K Oerline, Megan E V Caram, Phoebe A Tsao, Samuel R Kaufman, Brent K Hollenbeck, Vahakn B Shahinian. Risk of Metabolic and Cardiovascular Adverse Events With Abiraterone or Enzalutamide Among Men With Advanced Prostate Cancer. JNCI: Journal of the National Cancer Institute, 2022; DOI: 10.1093/jnci/djac081 Cite This Page: Michigan Medicine – University of Michigan. “Common prostate cancer medications may be less safe than previously thought.” ScienceDaily. ScienceDaily, 25 May 2022. . Michigan Medicine – University of Michigan. (2022, May 25). Common prostate cancer medications may be less safe than previously thought. ScienceDaily. Retrieved May 25, 2022 from https://ift.tt/0sb746x Michigan Medicine – University of Michigan. “Common prostate cancer medications may be less safe than previously thought.” ScienceDaily. https://ift.tt/0sb746x (accessed May 25, 2022).
With 6 more chemo cycles left, Asheesh desperately needs your help to fight blood cancer. His fruit seller father has no means to afford the remaining treatment to help his son survive. Donate now: https://bit.ly/3Lupq3n#Crowdfunding #GiveIndiaEstablished in 2000, GiveIndia is the largest and most trusted giving platform in India. Our community of 2M+ donors and 250+ corporate partners and brands have supported 2,500+ nonprofits, impacting 15M+ lives across India.Follow Us OnInstagram: https://instagram.com/give_indiaFacebook: https://facebook.com/giveindiaTwitter: https://twitter.com/GiveIndiaLinkedIn: https://in.linkedin.com/company/giveindiaRaise funds for a non-profit/cause or help a loved one through an urgent medical crisis. Raising funds on GiveIndia is quick and easy. Checkout: https://fundraisers.giveindia.org/
Novel approach could lead to treatment of devastating brain tumors Disclaimer :Copyright Disclaimer under section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, comment, news reporting, teaching, scholarship, education and research.Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. https://tinyurl.com/TodaySciencology#Science #Technology #Invention #ScienceDailyFindings from a seven-year research project suggests that there could be a new approach to treating one of the most common and devasting forms of brain cancer in adults — Glioblastoma Multiforme (GBM). In a peer-reviewed study published by BMC Cancer, scientists from the University of Surrey show that a short chain of amino acids (the HTL-001 peptide) is effective at targeting and inhibiting the function of a family of genes responsible for the growth of GBM — Hox genes. The study was conducted in cell and animal models. The HTL-001 peptide used in the study has undergone safety testing and is suitable for patient trials. These trials are now being considered in GBM and other cancers. Hardev Pandha, project lead and Professor of Medical Oncology at the University of Surrey, said: “People who suffer from Glioblastoma Multiforme have a five per cent survival rate over a five-year period — a figure that has not improved in decades. While we are still early in the process, our seven-year project offers a glimmer of hope for finding a solution to Hox gene dysregulation, which is associated with the growth of GBM and other cancers, and which has proven to be elusive as a target for so many years.” Ironically, Hox genes are responsible for the healthy growth of brain tissue but are ordinarily silenced at birth after vigorous activity in the growing embryo. However, if they are inappropriately ‘switched on’ again, their activity can lead to the progression of cancer. Hox gene dysregulation has long been recognised in GBM. The project was carried out in collaboration with the universities of Surrey, Leeds and Texas, and HOX Therapeutics, a University of Surrey start-up company based on the University’s Surrey Research Park. Professor Susan Short, co-author of the study from the University of Leeds, said: “We desperately need new treatment avenues for these aggressive brain tumours. Targeting developmental genes like the HOX genes that are abnormally switched on in the tumour cells could be a novel and effective way to stop glioblastomas growing and becoming life-threatening.” James Culverwell, CEO of HOX Therapeutics, said: “HOX Therapeutics is excited to be associated with this project and we hope that with our continuing support, this research will eventually lead to novel and effective treatments for both brain and other cancers where HOX gene over-expression is a clear therapeutic target.” make a difference: sponsored opportunity Story Source: Materials provided by University of Surrey. Note: Content may be edited for style and length. Journal Reference: Einthavy Arunachalam, William Rogers, Guy R. Simpson, Carla Möller-Levet, Gemma Bolton, Mohammed Ismael, Christopher Smith, Karl Keegen, Izhar Bagwan, Tim Brend, Susan C. Short, Bangxing Hong, Yoshihiro Otani, Balveen Kaur, Nicola Annels, Richard Morgan, Hardev Pandha. HOX and PBX gene dysregulation as a therapeutic target in glioblastoma multiforme. BMC Cancer, 2022; 22 (1) DOI: 10.1186/s12885-022-09466-8 Cite This Page: University of Surrey. “Novel approach could lead to treatment of devastating brain tumors.” ScienceDaily. ScienceDaily, 9 May 2022. . University of Surrey. (2022, May 9). Novel approach could lead to treatment of devastating brain tumors. ScienceDaily. Retrieved May 9, 2022 from https://ift.tt/hzRD9EH University of Surrey. “Novel approach could lead to treatment of devastating brain tumors.” ScienceDaily. https://ift.tt/hzRD9EH (accessed May 9, 2022).
Establishment of a pancreatic cancer animal model using the pancreas-targeted hydrodynamic gene…
I just wanted to say the reason for lack of content Three things. #1 I was diagnosed with stage 3C Colon Cancer and ive been so so sick off and on 2# Lack of energy and content. 3# I have tried so much lately but ive have failed in providing content + arizona is different than your typical summers elsewhere. We have africanized bees and rattlesnakes here. I don’t care about snakes i care about the bees. Today i tried to shoot four different locations for you all. I just say please share this video with others and hug your Wife, Husband, B/F, G/F or kids Time can be so short also again thanks for the 700 Subs.
13-year-old Harsh has blood cancer and his body is turning weak each day making it difficult for him to continue chemotherapy – making bone marrow transplant his last chance to recover. Please donate to save Harsh with timely treatment. Donate now: https://bit.ly/3hB0b2Y#Crowdfunding #GiveIndiaEstablished in 2000, GiveIndia is the largest and most trusted giving platform in India. Our community of 2M+ donors and 250+ corporate partners and brands have supported 2,500+ nonprofits, impacting 15M+ lives across India.Follow Us OnInstagram: https://instagram.com/give_indiaFacebook: https://facebook.com/giveindiaTwitter: https://twitter.com/GiveIndiaLinkedIn: https://in.linkedin.com/company/giveindiaRaise funds for a non-profit/cause or help a loved one through an urgent medical crisis. Raising funds on GiveIndia is quick and easy. Checkout: https://fundraisers.giveindia.org/
Researchers from the University of Maryland found that weight loss, even as little as one pound over five years, was associated with reduced risk of a condition that can lead to the disease.
2 years old baby is fighting with Blood Cancer | Fundraising for Ayushman | Plz help him 🙏🙏Transfer directly to the Bank account of this Fundraiser. Only INR transfers are allowed.Virtual A/C No-6999413500564978Virtual A/C Name-Debraj Naskar-KettoA/C Type-CurrentIFSC-YESB0CMSNOC(The digit after B is Zero and the letter after N is O for orange)Donate Via UPI or PaytmGoogle Pay – 9836883164Paytm – 9836883164Top Donors -Subhra Sarkar ₹ 2,500Mohona ₹ 1,000SRSritapa Roychowdhury ₹ 1,000Well Wisher ₹ 1,000Well Wisher ₹ 1,000 Link – https://m.facebook.com/story.php?story_fbid=1116904922405668&id=100022585114396&sfnsn=wiwspwa#cancer #cancersucks #cancersurvivor #chemo #chemotherapy #nhl #nonhodgkinslymphoma #lymphoma #survivor #warrior #fighter #cancerslayer #bloodcancer #boymom #standuptocancer #su2c #stemcells #stemcell #stemcelltransplant
After being diagnosed with deadly pancreatic cancer, a woman was added to her official treatment with an off-label regimen and lived longer with her condition than most.#Mypancreatic #cancerbeat #oddsI #msure #alternativetherapy #help In September 2018, my rib and back pain broke out almost overnight. I ignored it at first, sure I was doing too much ab workout in the gym. When the pain persists for a few weeks, I go to the doctor. She was a little concerned, but all my blood and urine tests were back to normal.After two months, the pain got worse and started waking me at night. I made an appointment with a physical therapist. Within 10 minutes of examining me, a shadow appeared on the therapist’s face. “I don’t want to alarm you, but this pain isn’t musculoskeletal,” she told me. “You need a CT scan. Today.”Later that day—the Wednesday before Thanksgiving—my husband Greg and I sat in our local hospital’s emergency department, waiting for scan results. When the ED doctor returned to my room, her tone was serious. “We found something we totally didn’t expect,” she said. “There is a suspicious mass on your pancreas that looks like cancer. I’m so, so sorry.”A chill shivered down my entire body. From my experience as a health writer, I already knew that pancreatic was one of the deadliest types of cancer I could have.Somehow, my brain immediately switched to medical reporter mode and I asked questions. I must have been in shock, but I managed to take extra-meticulous notes, almost as if my neatly written words let me take some control over the information I had just heard. When I look back at those pages now, I barely recognize my own handwriting.Courtesy of Teri CettinaWhat is pancreatic cancer?Pancreatic cancer is the third deadliest cancer in the United States. Around three in four patients die within a year of being diagnosed. And what makes this cancer especially sneaky is that its early symptoms are so vague: Abdominal or back aches. A little stomach discomfort. Some bloating. Stuff you might feel if you ate too much at dinner. Nothing you would take seriously at all.In addition, most common blood tests don’t detect pancreatic cancer. By the time the cancer is discovered, the tumor has usually grown quite large. It may also have spread outside the pancreas, to the liver, lungs or, more rarely, abdominal fluid that may have collected due to the cancer. This cancer is quick moving and deadly.In my case, the pancreatic tumor was about the size of a golf ball, but had not yet spread. However, it was wrapped so tightly around several aortic and liver-related blood vessels that they were almost completely blocked. Removing the tumor surgically was next to impossible. My only option was aggressive chemotherapy. It might extend my life, but it was not expected to cure me.Our shared future was dissolving in front of my eyes.But I understood none of this on the night before Thanksgiving. All I knew was that my life was forever changed. I felt that our daughters, ages 17 and 21, were still too young to lose their mother without it leaving a permanent scar. My husband and I had been married 29 years and were as close as we’d ever been. Now our shared future was dissolving in front of my eyes.At 3 a.m. on Thanksgiving morning, I got up, unable to sleep. I padded quietly downstairs to our dining room and set the table for dinner with our extended family. I folded napkins and laid out silverware and plates. I set out bowls for mashed potatoes, stuffing, gravy and vegetables and tucked tiny yellow sticky notes into each dish so I’d remember which was which.Then I gave up and dissolved onto the cool, hardwood floor. I lay down flat, my face touching the wood, and began to pray. “Please, God, give me time. Give me time to be with my daughters and Greg. Please give me more time.”This is what it feels like to be diagnosed with cancerUntil you actually experience it, you cannot possibly know how you’ll handle the news that you might be dying. My first reaction was, quite strangely, relief. I can let up now. I don’t have to work so hard at this thing called life, because it’s almost over, I thought to myself.I had not realized until my diagnosis how utterly exhausted I was. I’d spent the past decade dealing with the stress of caring for both of my aging parents (now deceased), my husband’s recent job loss, maintaining my own freelance writing business and worrying over various issues related to my daughters’ health and education. Looking back, I believe that this cycle of chronic stress could have encouraged the cancer to take hold. I had none of the common risk factors that could explain this deadly diagnosis.But within days of getting this frightening news, a spark of new energy ignited inside me. I wasn’t ready to die. I was determined to use every research skill I had learned throughout my writing career to prolong my own life.That was more than three years ago. The doctors initiall
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A dog with a large tumor on his back that was invisible to everyone here?The untreated melanoma had festered and was obviously very painful.Every day, Zina wandered the streets looking for bread crumbs and endured the pain alone.The results of the physical examination showed that the tumor on her back was in the terminal stage.There was also dry eye syndrome, swelling of the two mammary glands.When all the tests were ready, Zinaida would be sent for surgery.👉More about best dog rescue videos & channel touching your heart here:The dodo pet rescue: https://www.youtube.com/user/TheDodoSiteHowl Of A Dog: https://www.youtube.com/user/HowlOfADoganimal-safe shelter ://www.youtube.com/channel/UCATG2XaK8TOe3R9tsgwkqbQIf there are any copyright issues with any videos posted here i will remove them. Please contact my Email: firstname.lastname@example.orgThank you for watching! #rescuedog ,#animalrescue, #dogrescue
#JCILM #BrJohnsonSequeira #JCILMTestimony #prayersforhealing #healing #healingofcancer #healedofcancer #victoryovercancer #victoryoverBurkittLymphoma #Bible #believe #Faith #powerofGODAn awesome testimony of healing and victory over Burkitt Lymphoma using scriptures and focusing on God’s Word.Original link:https://www.youtube.com/watch?v=2rbEBQrau1Y JCILM GLOBAL REVIVAL SCHOOLVisit our website JCILM GLOBALhttp://jcilmglobal.info/For MP3 downloads and resources, please visit https://drive.google.com/drive/folders/1qkkabfAesSOdOSFGsUe_7Ld7RoIC68UcTo get WHITE BOOK (Confessions of Promises from Bible) in different languages please click the link below :https://drive.google.com/drive/folders/1xevneNlRcfDBDWimVzFHuOjysb9hlZYY?usp=sharingLearn about upcoming events : https://bit.ly/2VTKsEPJCILM MISSION : FREELY WE HAVE RECIVED FROM JESUS CHRIST; AND THEREFORE FREELY WE GIVE UNTO BRETHREN.⏪Watch Our Other Channels⏩JCILM Konkani : https://bit.ly/3shnd3oJCILM Marathi : https://bit.ly/2W0NIhPJCILM Hindi : https://bit.ly/2Ukhqh7JCILM Dubai : https://bit.ly/3iNPU4RJCILM Sri lanka : https://bit.ly/2XtLJDgJCILM Africa : https://bit.ly/2VUve2s JCILM Malayalam : https://bit.ly/2VOfWfTJCILM Mysore : https://bit.ly/2UiDwR0JCILM Chennai : https://bit.ly/3CSqP0yJCILM Ireland : https://bit.ly/3CSzeREFollow JCILM on Facebook : https://bit.ly/37JT57rFollow JCILM on Instagram : https://bit.ly/3DK3zT3Follow JCILM on Twitter : https://bit.ly/38I7ykE About us JCILM – JESUS CHRIST IS LORD MINISTRIES is a LAY GLOBAL MINISTRY founded in India by Brother Johnson Sequeira on the Good News of Jesus Christ through the Word of God.