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Zanubrutinib for R/R primary CNS lymphoma: the initial results of the PRiZM+ platform study [Video]

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Blood Cancer

Zanubrutinib for R/R primary CNS lymphoma: the initial results of the PRiZM+ platform study

Chris Fox, MBChB(Hons), MRCP, FRCPath, University of Nottingham, Nottingham, UK, outlines the initial results from the PRiZM+ Phase II platform study (ISRCTN90634455) of zanubrutinib in patients with relapsed/refractory (R/R) primary central nervous system (CNS) lymphoma. Dr Fox presents the findings of the zanubrutinib monotherapy cohort and highlights that, despite this being a difficult-to-treat patient population with a short duration of first response, the overall response rate (ORR) was encouraging. The PRiZM+ study will now look at zanubrutinib in combination with other agents. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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