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Assessing increased creatinine levels in patient with lung cancer receiving TKIs [Video]

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Pediatric Cancer

Assessing increased creatinine levels in patient with lung cancer receiving TKIs

Monica Chen, MD, Memorial Sloan Kettering Cancer Center, New York, NY, reports on patients with lung cancer having false decreases in renal function as a result of receiving tyrosine kinase inhibitors (TKIs) such as selpercatinib and entrectinib. Increased levels of creatinine as a result of these TKIs were found to cause this phenomenon, and alternative markers of renal function that do not affect creatinine levels include cystatin C. This interview took place at 2024 Targeted Therapies of Lung Cancer Meeting (TTLC 2024) in Santa Monica, CA.

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