DRP-104 with durvalumab in fibrolamellar hepatocellular carcinoma [Video]

Marina Baretti, MD, Johns Hopkins University School of Medicine, Baltimore, MD, gives an overview of a new Phase I/II trial (NCT06027086) using DRP-104 with durvalumab to treat fibrolamellar hepatocellular carcinoma (FLC). Using the glutamine antagonist to encourage metabolic reprogramming reduces immunity to immune checkpoint inhibitor (ICI) treatment in patients with FLC. This interview took place at American Association for Cancer Research (AACR) Annual Meeting 2024 in San Diego, CA.

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