E4112: MRI and gene expression optimization of local therapy for ductal carcinoma in situ [Video]

Seema Khan, MD, Northwestern Feinberg School of Medicine, Chicago, IL, discusses data coming from a prospective, single arm, multicenter study evaluating the impact of magnetic resonance imaging (MRI) and 12-gene expression assay on the optimization of radiotherapy for ductal carcinoma in situ (DCIS). This analysis included ipsilateral breast events (IBE) at 5-years. The 5 year IBE rate was reported as similar between the low DCIS Score (DS) group treated with wide local excision (WLE) alone versus the inter/hi DS group treated with WLE and radiation. Prior studies have shown a marked difference in IBE rates by DS with excision alone. Therefore, this study supports omitting radiotherapy post-surgery in DCIS patients with low DS, and it’s use in patients with inter/hi DS. This interview took place at the San Antonio Breast Cancer Symposium (SABCS) congress in San Antonio, TX.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.