FLT3-ITD-specific MRD predicts outcomes of chemotherapy in AML [Video]

Mark Levis, MD, PhD, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, discusses the QuANTUM-First trial (NCT02668653), which monitored measurable residual disease (MRD) levels using FLT3-ITD-specific assays in patients with acute myeloid leukemia (AML) following chemotherapy. Favorable treatment outcomes were observed in patients who achieved MRD negativity following two courses of chemotherapy, paving the way for personalized medicine based on post-treatment MRD levels. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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