Name: New model of key brain tumor feature could help scientists understand how to develop new treatments #BrainTumors #BrainCancer #BrainCancerSurvivalRates [Video]
Uploaded: 2024-03-01T18:46:31+00:00
Description: Researchers at the University of Michigan Health Rogel Cancer Center are exploiting a unique biological feature of glioblastoma to gain a better understanding o

New model of key brain tumor feature could help scientists understand how to develop new treatments [Video]

Newswise — New model of key brain tumor feature could help scientists understand how to develop new treatments

U-M team develops model showing how oncostreams form and behave – and how to inhibit them

ANN ARBOR, Michigan — Researchers at the University of Michigan Health Rogel Cancer Center are exploiting a unique biological feature of glioblastoma to gain a better understanding of how this puzzling brain cancer develops and how to target new treatments against it.

The team, led by senior author Pedro Lowenstein, M.D., Ph.D., Richard Schneider Collegiate Professor of Neurosurgery at Michigan Medicine, had previously identified oncostreams as a key feature in glioblastoma development and in more aggressive disease. These highly active, elongated, spindle-like cells move throughout tissue in complicated patterns. The accumulation of oncostreams found throughout a tumor serve as the basis for cancerous cells’ behavior, determining how tumors grow and invade normal tissue.

In this new study, published in Advanced Science, the team developed human …

Tags Brain Cancer, Brain Cancer Survival Rates, Brain Tumors