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REALITY-01: real-world use of trastuzumab deruxtecan in breast cancer [Video]

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Pediatric Cancer

REALITY-01: real-world use of trastuzumab deruxtecan in breast cancer

Jean-Yves Pierga, MD, PhD, Institut Curie, Paris, France, evaluates findings from the REALITY-01 study (NCT05149014) of trastuzumab deruxtecan, an antibody-drug conjugate, in patients with HER2+ metastatic breast cancer, who had received at least two prior anti-HER2 treatments. Interim results indicate a promising median progression-free survival and objective response rate, with a favorable safety profile aligning with DESTINY-Breast01 (NCT03248492) and 02 (NCT03523585) results. This interview took place at the 2024 European Society for Medical Oncology (ESMO) Breast Cancer Annual Congress in Berlin, Germany.

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