Categories
Blood Cancer

Personalized Cancer Treatment Just Got Harder [Video]

Go to https://NordPass.com/SCISHOW and use code SCISHOW to get 70% off a 2 year NordPass Premium plan plus 1 free month! It’s risk free with 30 day money-back guarantee!Scientists are working to develop personalized cancer treatments, but one obstacle in the way is figuring out how different cells react to one another.Hosted by: Hank GreenSciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow ———-Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow———-Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:Chris Peters, Matt Curls, Kevin Bealer, Jeffrey Mckishen, Jacob, Christopher R Boucher, Nazara, Jason A Saslow, charles george, Christoph Schwanke, Ash, Bryan Cloer, Silas Emrys, Eric Jensen, Adam Brainard, Piya Shedden, Jeremy Mysliwiec, Alex Hackman, GrowingViolet, Sam Lutfi, Alisa Sherbow, Dr. Melvin Sanicas, Melida Williams, Tom Mosner———-Looking for SciShow elsewhere on the internet?SciShow Tangents Podcast: http://www.scishowtangents.orgFacebook: http://www.facebook.com/scishowTwitter: http://www.twitter.com/scishowInstagram: http://instagram.com/thescishow———-Sources:https://www.nature.com/articles/s41586-021-04206-7https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651054/https://www.scimex.org/newsfeed/its-not-all-in-their-dna-cancer-cells-with-the-same-genome-can-behave-differentlyhttps://www.eurekalert.org/news-releases/937554?http://dx.doi.org/10.1016/j.celrep.2021.110115https://www.istockphoto.com/photo/set-iv-drip-fluid-intravenous-drop-saline-drip-hospital-room-medical-concept-gm1227586908-362112204https://commons.wikimedia.org/wiki/File:Myeloblast_with_Auer_rod_smear_2010-01-27.JPGhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358780/https://commons.wikimedia.org/wiki/File:Breast_cancer_cells.jpghttps://www.istockphoto.com/photo/cancer-cells-vis-gm1277229026-376503224https://www.istockphoto.com/photo/cancer-treatment-in-a-modern-medical-private-clinic-or-hospital-with-a-linear-gm1314465741-402674729https://www.istockphoto.com/photo/demotivated-students-in-a-lecture-hall-gm847311278-138908523https://www.istockphoto.com/photo/drinking-mouse-gm173542353-7748355https://www.istockphoto.com/photo/wild-mouse-sitting-on-hind-legs-gm531927696-94019573https://www.istockphoto.com/photo/white-mouse-4-gm89327997-6312157https://www.istockphoto.com/photo/the-girl-listens-attentively-with-her-palm-to-her-ear-close-up-on-pink-background-gm1266725568-371418329

Categories
Skin Cancer

The Common Mouth Microbe That Keeps Popping Up in Tumors [Video]

The Common Mouth Microbe That Keeps Popping Up in TumorsDisclaimer :Copyright Disclaimer under section 107 of the Copyright Act 1976, allowance is made for “fair use” for purposes such as criticism, comment, news reporting, teaching, scholarship, education and research.Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use. https://tinyurl.com/TodaySciencology#Science #Technology #Invention Might brushing your teeth protect against cancer? The suggestion looks like it belongs in the pages of an unreliable tabloid, but scientific evidence for the link is strong and growing.   Take head and neck cancer, which kills some 450,000 people worldwide every year. It’s associated with smoking and drinking alcohol, which is one reason why the most common form of the disease, oral squamous cell carcinoma (OSCC), tends to cluster in under resourced areas. But plenty of people diagnosed with OSCC say they never drank nor smoked, so researchers have been looking for other possible causes.  One likely candidate is gum disease. A series of studies have identified periodontitis, a bacterial infection that eats away soft tissue and eventually bone around teeth, as a risk factor for OSCC. That might be because the disease changes the behavior of usually benign bugs that live in the mouth.  A study published late last year, for example, showed that mice infected with oral bacteria developed significantly larger and more numerous tumors compared to those not infected.   “The moment they sense that there’s some problem in the mouth, or that there is a decrease in the immune system, they respond and attack, because they’re looking for food,” says Jorge Frias-Lopez, a microbiologist at the University of Florida’s school of dentistry who studies the link between the oral microbiome and cancer.  And of the 700 or so bacterial species typically found in our mouths, scientists studying OSCC have zeroed in on a spindle-shaped suspect called Fusobacterium nucleatum. It’s early days, but researchers think F. nucleatum could explain why gum disease is linked to the development of oral tumors.   “All of the signs are leaning towards that this bacterium is in some way involved,” says Daniel Slade, a biochemist at Virginia Tech who studies the role bacteria play in cancer. “But it’s still an open question and needs more research on whether it can initiate cancer, or whether or not it’s accelerating cancer.”   Bacteria and tumors  Infectious microbes are reckoned to contribute to some 20 percent of human tumors. Viruses tend to soak up most of the blame, from the common human papillomaviruses that lead to cervical cancer to hepatitis B and C, which raise the risk of liver cancer.  “The concept that bacteria are important in cancer is new,” says Yvonne Hernandez-Kapila, a periodontologist at the University of California, San Francisco. When a link between colon cancer and the bacteria H. pylori was discovered in the 1990s, it triggered a search for other pathogenic and perhaps carcinogenic types, she says. “Then large population studies began to see some associations between bacteria, especially oral bacteria, and some cancers.”  Such association studies make up the bulk of the evidence that currently links OSCC to F. nucleatum. Starting in 1998, research on people with cancer has shown time and again that levels of the bacteria and bacterial gene expression are higher in OSCC tumors than in normal tissue.  “Fusobacterium nucleatum is actually present in many people,” says Hernandez-Kapila. “However, the relative numbers increase in cancer patients. We’ve shown that in oral and head and neck cancer patients.”  Association studies can only identify a correlation between the bacteria and disease, and famously, correlation does not equal causation. Without longitudinal studies to examine whether people with higher numbers of the bacteria go on to develop higher rates of cancer, scientists struggle to determine whether the bugs perhaps cause and worsen the disease, or if they are simply found alongside tumors. “There might be a role for Fusobacterium in promoting cancers, but I think it’s a kind of chicken and egg question,” says Miguel Reis Ferreira, a clinical oncologist at Guys and St Thomas NHS Foundation Trust in London.   But scientists like Slade and Hernandez-Kapila believe that F. nucleatum does contribute to cancer. Th…

Categories
Blood Cancer

World-class research: Genomics England’s latest successes in cancer, rare diseases, and Covid-19 [Video]

In this session we present the most exciting results from our recent research efforts on Covid-19, cancer and rare diseases.

Categories
Colon Cancer

Novel Therapeutic Approach: Breaking the Wall of Ineffective Cancer Therapies | Ana Montalban Arques [Video]

Our novel approach applying bacteria as a stand-alone therapy for colon cancer is, to the best of our knowledge, the only therapeutic approach that shows striking efficacy of bacteria as monotherapy.Learn more about Falling Walls Lab and how you can participate here: https://falling-walls.com/lab

Categories
Prostate Cancer

Mass Spectrometry: Breaking the Wall of Prostate Cancer Treatment Resistance | Chamikara Liyanage [Video]

Identifying small proteins produced by prostate cancer, using a novel mass-spectrometry method. Exploring the role of small proteins in treatment resistance, using cell-based and animal model studies.Learn more about Falling Walls Lab and how you can participate here: https://falling-walls.com/lab

Categories
Blood Cancer

Hodgkin’s lymphoma [USMLE Quick Review] #shorts [Video]

Hodgkin’s lymphoma — formerly known as Hodgkin’s disease — is a cancer of the lymphatic system, which is part of your immune system. It may affect people of any age, but is most common in people between 20 and 40 years old and those over 55.In Hodgkin’s lymphoma, cells in the lymphatic system grow abnormally and may spread beyond it.#shorts✔ Subscribe: https://tinyurl.com/medxclusiveSUB✔ Blog: https://medXclusive.orgAny Video Clips Used — are used with permission or under fair use:- Section 105 of the Copyright Act (17 U.S.C. § 105).- public domain according to the CC0 license, or- free to use commercially.————–Subscribe to us for Medicine, Preventive Medicine, Board Exams’ HighYield Review (USMLE, NCLEX, COMLEX,…), Health Tips, Health Care News, and Patient Awareness. If you are a doctor, future doctor, nurse, future nurse, paramedics, or just a good Samaritan, remember this – We are all in this together. Health care is about “care”–first and foremost–as the name suggests. Our goal is to provide free medical education with up-to-date medical information through notes (on the medXclusive blog), and through our YouTube videos; so that students could have a “prep course” without having to pay for it. The goal is to make sure that money (or lack thereof) is not the reason anyone scores less than those who can afford to spend these thousands of dollars. Hope you support us in our journey!——–Medicine is the science and practice of establishing the diagnosis, prognosis, treatment, and prevention of disease. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others- The United States Medical Licensing Examination (USMLE) is a three-step examination for medical licensure in the United States and is sponsored by the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Physicians with an MD degree are required to pass this examination before being permitted to practice medicine in the United States.- The Comprehensive Osteopathic Medical Licensing Examination of the United States (COMLEX-USA) is a series of three osteopathic medical licensing examinations administered by the National Board of Osteopathic Medical Examiners (NBOME) similar to the United States Medical Licensing Examination (USMLE). COMLEX-USA is the most common pathway by which osteopathic physicians (D.O.s) apply for medical licensure, and is accepted in all 50 states. The 3-digit standard scores of COMLEX-USA Level 1, Level 2- Cognitive Evaluation (CE), and Level 3 have a range of 9-999 and a mean of 500. Most candidates score between 250 and 800. 400 is the minimum passing score for COMLEX-USA Levels 1 and 2; 350 for COMLEX-USA Level 3.- The National Council Licensure Examination (NCLEX) is a nationwide examination for the licensing of nurses in the United States and Canada since 1982 and 2015, respectively. There are two types, the NCLEX-RN and the NCLEX-PN. After graduation from a school of nursing, one takes the NCLEX exam to receive a nursing license. A nursing license gives an individual permission to practice nursing, granted by the state where they met the requirements. The NCLEX-RN uses the five-step nursing process. Each of the questions will fall into one of the five steps: assessment, diagnosis, planning, implementation, and evaluation.Hi, Al. This video is about medical education — medicine, research, health, and healthcare related exams. Please show it to people who will like it. Thank you.

Categories
Skin Cancer

Pronunciation of the word(s) “Acral-lentiginous Melanoma”. [Video]

Pronunciation of the word(s) “Acral-lentiginous Melanoma”.Subscribe to the Channel to stay updated with the latest terms that are added on a regular basis.Thank you!

Categories
Breast Cancer

Pronunciation of the word(s) “Mammogram”. [Video]

Pronunciation of the word(s) “Mammogram”.Subscribe to the Channel to stay updated with the latest terms that are added on a regular basis.Thank you!

Categories
Blood Cancer

Follicular Lymphoma [USMLE Quick Review] #shorts [Video]

Follicular lymphoma (FL) is typically a slow-growing or indolent form of non- Hodgkin lymphoma (NHL) that arises from B-lymphocytes, making it a B-cell lymphoma. This lymphoma subtype accounts for 20 to 30 percent of all NHL cases.#shorts✔ Subscribe: https://tinyurl.com/medxclusiveSUB✔ Blog: https://medXclusive.orgAny Video Clips Used — are used with permission or under fair use:- Section 105 of the Copyright Act (17 U.S.C. § 105).- public domain according to the CC0 license, or- free to use commercially.————–Subscribe to us for Medicine, Preventive Medicine, Board Exams’ HighYield Review (USMLE, NCLEX, MCAT,…), Health Tips, Health Care News, and Patient Awareness. If you are a doctor, future doctor, nurse, future nurse, paramedics, or just a good Samaritan, remember this – We are all in this together. Health care is about “care”–first and foremost–as the name suggests. Our goal is to provide free medical education with up-to-date medical information through notes (on the medXclusive blog), and through our YouTube videos; so that students could have a “prep course” without having to pay for it. The goal is to make sure that money (or lack thereof) is not the reason anyone scores less than those who can afford to spend these thousands of dollars. Hope you support us in our journey!——–Medicine is the science and practice of establishing the diagnosis, prognosis, treatment, and prevention of disease. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others- The United States Medical Licensing Examination (USMLE) is a three-step examination for medical licensure in the United States and is sponsored by the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Physicians with an MD degree are required to pass this examination before being permitted to practice medicine in the United States.- The Comprehensive Osteopathic Medical Licensing Examination of the United States (COMLEX-USA) is a series of three osteopathic medical licensing examinations administered by the National Board of Osteopathic Medical Examiners (NBOME) similar to the United States Medical Licensing Examination (USMLE). COMLEX-USA is the most common pathway by which osteopathic physicians (D.O.s) apply for medical licensure, and is accepted in all 50 states. The 3-digit standard scores of COMLEX-USA Level 1, Level 2- Cognitive Evaluation (CE), and Level 3 have a range of 9-999 and a mean of 500. Most candidates score between 250 and 800. 400 is the minimum passing score for COMLEX-USA Levels 1 and 2; 350 for COMLEX-USA Level 3.- The National Council Licensure Examination (NCLEX) is a nationwide examination for the licensing of nurses in the United States and Canada since 1982 and 2015, respectively. There are two types, the NCLEX-RN and the NCLEX-PN. After graduation from a school of nursing, one takes the NCLEX exam to receive a nursing license. A nursing license gives an individual permission to practice nursing, granted by the state where they met the requirements. The NCLEX-RN uses the five-step nursing process. Each of the questions will fall into one of the five steps: assessment, diagnosis, planning, implementation, and evaluation.