Featuring perspectives from Prof Solange Peters and Drs Zofia Piotrowska and Gregory J Riely, including the following topics:
• Current and Future Treatment of Non-Small Cell Lung Cancer (NSCLC) with Targetable Mutations, Including ALK and ROS1
• Introduction: Targeted treatment in the adjuvant setting (0:00)
• Case: A man in his late 60s with metastatic adenosquamous carcinoma of the lung — PD-L1 >95%, ROS1 rearrangement — Margaret Deutsch, MD (11:55)
• Case: A woman in her mid-70s with metastatic adenocarcinoma of the lung and cancer in the right breast — TMB 14 mut/Mb, ALK mutation — Raymond Lobins, DO (19:15)
• Management Strategies for Patients with NSCLC with RET Fusions or MET Alterations
• Case: A woman in her early 60s with metastatic adenocarcinoma of the lung — PD-L1 0%, RET KIF5B fusion — Mohamed K Mohamed, MD, PhD (24:40)
• Key Data Guiding the Management of Metastatic NSCLC with EGFR Mutations
• Case: A woman in her mid-60s with metastatic adenocarcinoma of the lung — PD-L1 60%, EGFR exon 19 deletion — Gigi Chen, MD (29:15)
• Case: A man in his early 70s with metastatic NSCLC — EGFR L858R mutation — Maria Regina Flores, MD (36:53)
• Therapeutic Approaches for Patients with NSCLC with HER2 or KRAS Mutations
• Case: A woman in her early 60s with recurrent metastatic adenocarcinoma of the lung — HER2 mutation — Dr Lobins (43:20)
• Case: A woman in her mid-40s with metastatic adenocarcinoma of the lung — KRAS G12C mutation — Sulfi Ibrahim, MD (51:03)
CME information and select publications (http://m.researchtopractice.com/ASCOTargetedNSCLC21/Video)