Post-transplant PD1 blockade plus autologous lymphocytes in R/R HL [Video]

Fabio Guolo, MD, University of Genoa, Genoa, Italy, introduces a study evaluating the efficacy of PD1 blockade with nivolumab or pembrolizumab alongside autologous lymphocyte reinfusion following chemotherapy and autologous stem cell transplantation (autoSCT) in patients with relapsed/refractory Hodgkin lymphoma (HL). The study found a complete response (CR) rate of 100%, with the underlying biological mechanism involving the expansion of natural killer (NK) cells. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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