Real-world outcomes of 177Lu-PSMA-617 in mCRPC [Video]

Hannah McManus, MD, Duke Cancer Institute, Duke University School of Medicine, Durham, NC, briefly discusses the novel radiopharmaceutical lutetium-177 prostate-specific membrane antigen 617 (177Lu-PSMA-617) as an excellent treatment option for patients with metastatic castration-resistant prostate cancer (mCRPC). Summarizing a recent paper assessing real-world clinical outcomes of treatment with 177Lu-PSMA-617 for mCRPC, Dr McManus notes the highly promising prostate specific antigen (PSA) response rates. Remarkably, a significant proportion of patients demonstrated a PSA50 and PSA90 response, demonstrating the clinical efficacy of 177Lu-PSMA-617 as an effective treatment for patients with mCRPC. This interview took place at the 2024 American Association for Cancer Research (AACR) in San Diego, CA.

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